Assessment of Phytochemial and Antimicrobial Activity of Secondary Metabolites of Plant Citrullus Colocynthis L
Keywords:
Citrullus colocynthis, antimicrobial effect, inhibition zone, resistanceAbstract
Low susceptibility to standard antimicrobial drugs and resistance to antibiotics represent a significant challenge to develop effective treatment. Many natural compounds were found to inhibit bacterial and fungal infection. In this study different solvent extracts was prepared from different parts of Citrullus colocynthis plant such as pulp, seeds and leaves. The phytochemical constituents of plant were carried out by using methanol and acetone were found tobe such as alkaloids, glycosides, cucurbitacins, flavanoids, saponin and trace of tannin .The raw extracts of both solvents were evaluated for their antimicrobial properties using agar disc diffusion method. The antimicrobial activity of crude ethanolic and acetone extracts were evaluated against the some human and plant pathogens. The result obtained showed wide range of anti-microbial activity. This study offers new opportunities for development new drugs with minimal side effect and high pharmacological efficiency.
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